Dan Uggla extended his hitting streak to 33 games with a first-inning single, but the offense let down Derek Lowe, leaving 11 runners on base. The Cubs took a 1-0 lead in the first, but Uggla's fourth-inning home run off Randy Wells tied the game.
The Cubs retook the lead in the fifth. After Lowe retired the first two hitters, singles from Darwin Barney and Aramis Ramirez brought up Carlos Pena and he drove them both in with a double. They tacked on two more in the sixth when Tyler Colvin tripled on a fly ball Michael Bourn couldn't hang on to and with Geovany Soto batting, scored on a wide throw to home from Chipper Jones.
Atlanta tallied a single run in the bottom of the sixth to cut the lead to 5-2, but the Cubs kept adding more in the eighth. An infield single and a dropped fly ball by Martin Prado gave Chicago runners at the corners with one out. Pinch-hitter Blake DeWitt drove in pinch-runner Tony Campana with a fielder's choice followed by run-scoring singles from Barney and Starlin Castro for an 8-2 advantage. Both Castro and Barney recorded four hits in the game.
Trailing 8-3 in the ninth, the Braves managed to load the bases with one out, but could only push across one run against Carlos Marmol. The Braves were only 2-for-14 with runners in scoring position.